Aurora Kinase A is critical for the Nkx6.1 mediated β-cell proliferation pathway

Por Hobson, Amanda, Draney, Carrie, Stratford, Andrew, Becker, Thomas C, Lu, Danhong, Arlotto, Michelle, Tessem, Jeffery S
Publicado no Islets (2015)

Small Interfering RNA–Mediated Suppression of Proislet Amyloid Polypeptide Expression Inhibits Islet Amyloid Formation and Enhances Survival of Human Islets in Culture

Por Marzban, Lucy, Tomas, Alejandra, Becker, Thomas C., Rosenberg, Lawrence, Oberholzer, Jose, Fraser, Paul E., Halban, Philippe A., Verchere, C. Bruce
Publicado em 2008

Erratum. Small Interfering RNA—Mediated Suppression of Proislet Amyloid Polypeptide Expression Inhibits Islet Amyloid Formation and Enhances Survival of Human Islets in Culture. Di...

Por Marzban, Lucy, Tomas, Alejandra, Becker, Thomas C., Rosenberg, Lawrence, Oberholzer, Jose, Fraser, Paul E., Halban, Philippe A., Verchere, C. Bruce
Publicado no Diabetes (2016)

Relationship among Brain and Blood Glucose Levels and Spontaneous and Glucoprivic Feeding

Por Dunn-Meynell, Ambrose A., Sanders, Nicole M., Compton, Douglas, Becker, Thomas C., Eiki, Jun-ichi, Zhang, Bei B., Levin, Barry E.
Publicado em 2009

Cooperative Transcriptional Regulation of the Essential Pancreatic Islet Gene NeuroD1 (Beta2) by Nkx2.2 and Neurogenin 3

Por Anderson, Keith R., Torres, Ciara A., Solomon, Keely, Becker, Thomas C., Newgard, Christopher B., Wright, Christopher V., Hagman, James, Sussel, Lori
Publicado em 2009

Chronic Suppression of Acetyl-CoA Carboxylase 1 in β-Cells Impairs Insulin Secretion via Inhibition of Glucose Rather Than Lipid Metabolism

Por Ronnebaum, Sarah M., Joseph, Jamie W., Ilkayeva, Olga, Burgess, Shawn C., Lu, Danhong, Becker, Thomas C., Sherry, A. Dean, Newgard, Christopher B.
Publicado em 2008

The Mitochondrial 2-Oxoglutarate Carrier Is Part of a Metabolic Pathway That Mediates Glucose- and Glutamine-stimulated Insulin Secretion

Por Odegaard, Matthew L., Joseph, Jamie W., Jensen, Mette V., Lu, Danhong, Ilkayeva, Olga, Ronnebaum, Sarah M., Becker, Thomas C., Newgard, Christopher B.
Publicado em 2010

A Pdx-1-Regulated Soluble Factor Activates Rat and Human Islet Cell Proliferation

Por Hayes, Heather L., Zhang, Lu, Becker, Thomas C., Haldeman, Jonathan M., Stephens, Samuel B., Arlotto, Michelle, Moss, Larry G., Newgard, Christopher B., Hohmeier, Hans E.
Publicado no Mol Cell Biol (2016)

Stimulation of Human and Rat Islet β-Cell Proliferation with Retention of Function by the Homeodomain Transcription Factor Nkx6.1

Por Schisler, Jonathan C., Fueger, Patrick T., Babu, Daniella A., Hohmeier, Hans E., Tessem, Jeffery S., Lu, Danhong, Becker, Thomas C., Naziruddin, Bashoo, Levy, Marlon, Mirmira, Raghavendra G., Newgard, Christopher B.
Publicado em 2008

The Brain–to–Pancreatic Islet Neuronal Map Reveals Differential Glucose Regulation From Distinct Hypothalamic Regions

Por Rosario, Wilfredo, Singh, Inderroop, Wautlet, Arnaud, Patterson, Christa, Flak, Jonathan, Becker, Thomas C., Ali, Almas, Tamarina, Natalia, Philipson, Louis H., Enquist, Lynn W., Myers, Martin G., Rhodes, Christopher J.
Publicado no Diabetes (2016)

The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells

Por Schisler, Jonathan C., Jensen, Per Bo, Taylor, David G., Becker, Thomas C., Knop, Filip Krag, Takekawa, Shiro, German, Michael, Weir, Gordon C., Lu, Danhong, Mirmira, Raghavendra G., Newgard, Christopher B.
Publicado em 2005

Coordinated Regulatory Variation Associated with Gestational Hyperglycemia Regulates Expression of the Novel Hexokinase HKDC1

Por Guo, Cong, Ludvik, Anton E., Arlotto, Michelle E., Hayes, M. Geoffrey, Armstrong, Loren L., Scholtens, Denise M., Brown, Christopher D., Newgard, Christopher B., Becker, Thomas C., Layden, Brian T., Lowe, William L., Reddy, Timothy E.
Publicado no Nat Commun (2015)

Regulation of Skeletal Muscle Oxidative Capacity and Insulin Signaling by the Mitochondrial Rhomboid Protease PARL

Por Civitarese, Anthony E., MacLean, Paul S., Carling, Stacy, Kerr-Bayles, Lyndal, McMillan, Ryan P., Pierce, Anson, Becker, Thomas C., Moro, Cedric, Finlayson, Jean, Lefort, Natalie, Newgard, Christopher B., Mandarino, Lawrence, Cefalu, William, Walder, Ken, Collier, Greg R., Hulver, Matthew W., Smith, Steven R., Ravussin, Eric
Publicado em 2010

CCAAT/Enhancer-binding Protein β Deletion Reduces Adiposity, Hepatic Steatosis, and Diabetes in Lepr(db/db) Mice()

Por Schroeder-Gloeckler, Jill M., Rahman, Shaikh Mizanoor, Janssen, Rachel C., Qiao, Liping, Shao, Jianhua, Roper, Michael, Fischer, Stephanie J., Lowe, Erin, Orlicky, David J., McManaman, James L., Palmer, Carol, Gitomer, William L., Huang, Wan, O’Doherty, Robert M., Becker, Thomas C., Klemm, Dwight J., Jensen, Dalan R., Pulawa, Leslie K., Eckel, Robert H., Friedman, Jacob E.
Publicado em 2007

Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas

Por Wang, Huan, Bender, Aaron, Wang, Peng, Karakose, Esra, Inabnet, William B., Libutti, Steven K., Arnold, Andrew, Lambertini, Luca, Stang, Micheal, Chen, Herbert, Kasai, Yumi, Mahajan, Milind, Kinoshita, Yayoi, Fernandez-Ranvier, Gustavo, Becker, Thomas C., Takane, Karen K., Walker, Laura A., Saul, Shira, Chen, Rong, Scott, Donald K., Ferrer, Jorge, Antipin, Yevgeniy, Donovan, Michael, Uzilov, Andrew V., Reva, Boris, Schadt, Eric E., Losic, Bojan, Argmann, Carmen, Stewart, Andrew F.
Publicado no Nat Commun (2017)