Aurora Kinase A is critical for the Nkx6.1 mediated β-cell proliferation pathway

Type 1 and type 2 diabetes are ultimately characterized by depleted β-cell mass. Characterization of the molecular pathways that control β-cell proliferation could be harnessed to restore these cells. The homeobox β-cell transcription factor Nkx6.1 induces β-cell proliferation by activating the orph...

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Detalhes bibliográficos
Publicado no:Islets
Main Authors: Hobson, Amanda, Draney, Carrie, Stratford, Andrew, Becker, Thomas C, Lu, Danhong, Arlotto, Michelle, Tessem, Jeffery S
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588548/
https://ncbi.nlm.nih.gov/pubmed/26030060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19382014.2015.1027854
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