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Postnatal β-Cell Proliferation and Mass Expansion Is Dependent on the Transcription Factor Nkx6.1

All forms of diabetes are characterized by a loss of functional β-cell mass, and strategies for expanding β-cell mass could have significant therapeutic benefit. We have recently identified the transcription factor Nkx6.1 as an essential maintenance factor of the functional β-cell state. In addition...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Diabetes
Päätekijät: Taylor, Brandon L., Benthuysen, Jacqueline, Sander, Maike
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Diabetes Association 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338594/
https://ncbi.nlm.nih.gov/pubmed/25277396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0684
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