CAR T cells take centre stage

Autor Beavis, Paul A, Darcy, Phillip K
Vydáno v Clin Transl Immunology (2019)

A Novel Target Antigen for the Treatment of Acute Myeloid Leukemia by CAR T Cells

Autor Beavis, Paul A., Sek, Kevin, Darcy, Phillip K.
Vydáno v Mol Ther (2017)

A(2A) blockade enhances anti-metastatic immune responses

Autor Beavis, Paul A, Milenkovski, Nicole, Stagg, John, Smyth, Mark J, Darcy, Phillip K
Vydáno 2013

Switching on the green light for chimeric antigen receptor T‐cell therapy

Autor Mardiana, Sherly, Lai, Junyun, House, Imran Geoffrey, Beavis, Paul Andrew, Darcy, Phillip Kevin
Vydáno v Clin Transl Immunology (2019)

A New Safety Approach Allowing Reversible Control of CAR T Cell Responses

Autor Chen, Amanda X.Y., House, Imran G., Beavis, Paul A., Darcy, Phillip K.
Vydáno v Mol Ther (2020)

Activation of p38 mitogen-activated protein kinase is critical step for acquisition of effector function in cytokine-activated T cells, but acts as a negative regulator in T cells...

Autor Li, Ching, Beavis, Paul, Palfreeman, Andrew C, Amjadi, Parisa, Kennedy, Alan, Brennan, Fionula M
Vydáno 2011

Targeting Adenosine Receptor Signaling in Cancer Immunotherapy

Autor Sek, Kevin, Mølck, Christina, Stewart, Gregory D., Kats, Lev, Darcy, Phillip K., Beavis, Paul A.
Vydáno v Int J Mol Sci (2018)

CD73 promotes anthracycline resistance and poor prognosis in triple negative breast cancer

Autor Loi, Sherene, Pommey, Sandra, Haibe-Kains, Benjamin, Beavis, Paul A., Darcy, Phillip K., Smyth, Mark J., Stagg, John
Vydáno 2013

Relevance of tumor-infiltrating lymphocytes in breast cancer

Autor Dushyanthen, Sathana, Beavis, Paul A., Savas, Peter, Teo, Zhi Ling, Zhou, Chenhao, Mansour, Mariam, Darcy, Phillip K., Loi, Sherene
Vydáno v BMC Med (2015)

CD73: A potential biomarker for anti-PD-1 therapy

Autor Beavis, Paul A, Slaney, Clare Y, Milenkovski, Nicole, Henderson, Melissa A, Loi, Sherene, Stagg, John, Kershaw, Michael H, Darcy, Phillip K
Vydáno v Oncoimmunology (2015)

Resistance to regulatory T cell-mediated suppression in rheumatoid arthritis can be bypassed by ectopic foxp3 expression in pathogenic synovial T cells

Autor Beavis, Paul A., Gregory, Bernard, Green, Patricia, Cribbs, Adam P., Kennedy, Alan, Amjadi, Parisa, Palfreeman, Andrew C., Feldmann, Marc, Brennan, Fionula M.
Vydáno 2011

Cross-talk between tumors can affect responses to therapy

Autor Devaud, Christel, John, Liza B, Westwood, Jennifer A, Yong, Carmen SM, Beavis, Paul A, Schwendener, Reto A, Darcy, Phillip K, Kershaw, Michael H
Vydáno v Oncoimmunology (2015)

Blockade of A(2A) receptors potently suppresses the metastasis of CD73(+) tumors

Autor Beavis, Paul A., Divisekera, Upulie, Paget, Christophe, Chow, Melvyn T., John, Liza B., Devaud, Christel, Dwyer, Karen, Stagg, John, Smyth, Mark J., Darcy, Phillip K.
Vydáno 2013

T cell inhibitory mechanisms in a model of aggressive Non-Hodgkin's Lymphoma

Autor Hilmenyuk, Tamara, Ruckstuhl, Carla A., Hayoz, Michael, Berchtold, Christian, Nuoffer, Jean-Marc, Solanki, Shyam, Keun, Hector C., Beavis, Paul A., Riether, Carsten, Ochsenbein, Adrian F.
Vydáno v Oncoimmunology (2017)

A study of the molecular mechanism of binding kinetics and long residence times of human CCR5 receptor small molecule allosteric ligands

Autor Swinney, David C, Beavis, Paul, Chuang, Kai-Ting, Zheng, Yue, Lee, Ina, Gee, Peter, Deval, Jerome, Rotstein, David M, Dioszegi, Marianna, Ravendran, Palani, Zhang, Jun, Sankuratri, Surya, Kondru, Rama, Vauquelin, Georges
Vydáno 2014

Tissue‐specific tumor microenvironments influence responses to immunotherapies

Autor Oliver, Amanda J, Davey, Ashleigh S, Keam, Simon P, Mardiana, Sherly, Chan, Jack D, von Scheidt, Bianca, Beavis, Paul A, House, Imran G, Van Audernaerde, Jonas RM, Darcy, Phillip K, Kershaw, Michael H, Slaney, Clare Y
Vydáno v Clin Transl Immunology (2019)

PTPN2 phosphatase deletion in T cells promotes anti‐tumour immunity and CAR T‐cell efficacy in solid tumours

Autor Wiede, Florian, Lu, Kun‐Hui, Du, Xin, Liang, Shuwei, Hochheiser, Katharina, Dodd, Garron T, Goh, Pei K, Kearney, Conor, Meyran, Deborah, Beavis, Paul A, Henderson, Melissa A, Park, Simone L, Waithman, Jason, Zhang, Sheng, Zhang, Zhong‐Yin, Oliaro, Jane, Gebhardt, Thomas, Darcy, Phillip K, Tiganis, Tony
Vydáno v EMBO J (2019)

Targeting the adenosine 2A receptor enhances chimeric antigen receptor T cell efficacy

Autor Beavis, Paul A., Henderson, Melissa A., Giuffrida, Lauren, Mills, Jane K., Sek, Kevin, Cross, Ryan S., Davenport, Alexander J., John, Liza B., Mardiana, Sherly, Slaney, Clare Y., Johnstone, Ricky W., Trapani, Joseph A., Stagg, John, Loi, Sherene, Kats, Lev, Gyorki, David, Kershaw, Michael H., Darcy, Phillip K.
Vydáno v J Clin Invest (2017)

BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1

Autor Hogg, Simon J., Vervoort, Stephin J., Deswal, Sumit, Ott, Christopher J., Li, Jason, Cluse, Leonie A., Beavis, Paul A., Darcy, Phillip K., Martin, Benjamin P., Spencer, Andrew, Traunbauer, Anna K., Sadovnik, Irina, Bauer, Karin, Valent, Peter, Bradner, James E., Zuber, Johannes, Shortt, Jake, Johnstone, Ricky W.
Vydáno v Cell Rep (2017)

Agonist immunotherapy restores T cell function following MEK inhibition improving efficacy in breast cancer

Autor Dushyanthen, Sathana, Teo, Zhi Ling, Caramia, Franco, Savas, Peter, Mintoff, Christopher P., Virassamy, Balaji, Henderson, Melissa A., Luen, Stephen J., Mansour, Mariam, Kershaw, Michael H., Trapani, Joseph A., Neeson, Paul J., Salgado, Roberto, McArthur, Grant A., Balko, Justin M., Beavis, Paul A., Darcy, Phillip K., Loi, Sherene
Vydáno v Nat Commun (2017)