Blockade of A(2A) receptors potently suppresses the metastasis of CD73(+) tumors

CD73 inhibits antitumor immunity through the activation of adenosine receptors expressed on multiple immune subsets. CD73 also enhances tumor metastasis, although the nature of the immune subsets and adenosine receptor subtypes involved in this process are largely unknown. In this study, we revealed...

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Detalhes bibliográficos
Main Authors: Beavis, Paul A., Divisekera, Upulie, Paget, Christophe, Chow, Melvyn T., John, Liza B., Devaud, Christel, Dwyer, Karen, Stagg, John, Smyth, Mark J., Darcy, Phillip K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767556/
https://ncbi.nlm.nih.gov/pubmed/23964122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308209110
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