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Blockade of A(2A) receptors potently suppresses the metastasis of CD73(+) tumors

CD73 inhibits antitumor immunity through the activation of adenosine receptors expressed on multiple immune subsets. CD73 also enhances tumor metastasis, although the nature of the immune subsets and adenosine receptor subtypes involved in this process are largely unknown. In this study, we revealed...

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Bibliografiska uppgifter
Huvudupphovsmän: Beavis, Paul A., Divisekera, Upulie, Paget, Christophe, Chow, Melvyn T., John, Liza B., Devaud, Christel, Dwyer, Karen, Stagg, John, Smyth, Mark J., Darcy, Phillip K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767556/
https://ncbi.nlm.nih.gov/pubmed/23964122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308209110
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