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Co-blockade of immune checkpoints and adenosine A(2A) receptor suppresses metastasis
Immunosuppressive pathways active within the tumor microenvironment must be targeted in combination to sufficiently bolster antitumor immune defenses. Inhibition of A(2A) adenosine receptor signaling in combination with immune checkpoint blockade enhances CD8(+) T and NK cell anti-metastatic activit...
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| Publicado no: | Oncoimmunology |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4292728/ https://ncbi.nlm.nih.gov/pubmed/25941583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.958952 |
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