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Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis
Extracellular adenosine is a potent immunosuppressor that accumulates during tumor growth. We performed proof-of-concept studies investigating the therapeutic potential and mechanism of action of monoclonal antibody (mAb)-based therapy against CD73, an ecto-enzyme overexpressed on breast-cancer cell...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824381/ https://ncbi.nlm.nih.gov/pubmed/20080644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908801107 |
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