Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis

Extracellular adenosine is a potent immunosuppressor that accumulates during tumor growth. We performed proof-of-concept studies investigating the therapeutic potential and mechanism of action of monoclonal antibody (mAb)-based therapy against CD73, an ecto-enzyme overexpressed on breast-cancer cell...

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Detaylı Bibliyografya
Asıl Yazarlar: Stagg, John, Divisekera, Upulie, McLaughlin, Nicole, Sharkey, Janelle, Pommey, Sandra, Denoyer, Delphine, Dwyer, Karen M., Smyth, Mark J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2010
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824381/
https://ncbi.nlm.nih.gov/pubmed/20080644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908801107
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