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The double-edge sword effect of anti-CD73 cancer therapy

We and others have identified CD73 as a new cancer target. I hereafter discuss that targeted blockade of CD73 has the effect of a “double-edge sword,” able on the one hand to rescue endogenous adaptive anti-tumor immune responses, and on the other hand, inhibit the metastatic potential of tumor cell...

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Detalhes bibliográficos
Autor principal: Stagg, John
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376997/
https://ncbi.nlm.nih.gov/pubmed/22720247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.1.2.18101
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