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ISG15: A double edged sword in cancer

Interferon-Stimulated Gene 15 (ISG15) transcript is aberrantly expressed in most human malignancies, suggesting that it has a protumor function. However, at the protein level ISG15 has both protumor and immunomodulatory antitumor functions. Therapeutic strategies to maximize the latter may benefit c...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Autor principal: Desai, Shyamal D
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635879/
https://ncbi.nlm.nih.gov/pubmed/26587329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1052935
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