Targeting the adenosine 2A receptor enhances chimeric antigen receptor T cell efficacy

Chimeric antigen receptor (CAR) T cells have been highly successful in treating hematological malignancies, including acute and chronic lymphoblastic leukemia. However, treatment of solid tumors using CAR T cells has been largely unsuccessful to date, partly because of tumor-induced immunosuppressiv...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Beavis, Paul A., Henderson, Melissa A., Giuffrida, Lauren, Mills, Jane K., Sek, Kevin, Cross, Ryan S., Davenport, Alexander J., John, Liza B., Mardiana, Sherly, Slaney, Clare Y., Johnstone, Ricky W., Trapani, Joseph A., Stagg, John, Loi, Sherene, Kats, Lev, Gyorki, David, Kershaw, Michael H., Darcy, Phillip K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330718/
https://ncbi.nlm.nih.gov/pubmed/28165340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI89455
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados