Targeting the adenosine 2A receptor enhances chimeric antigen receptor T cell efficacy

Chimeric antigen receptor (CAR) T cells have been highly successful in treating hematological malignancies, including acute and chronic lymphoblastic leukemia. However, treatment of solid tumors using CAR T cells has been largely unsuccessful to date, partly because of tumor-induced immunosuppressiv...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Clin Invest
Κύριοι συγγραφείς: Beavis, Paul A., Henderson, Melissa A., Giuffrida, Lauren, Mills, Jane K., Sek, Kevin, Cross, Ryan S., Davenport, Alexander J., John, Liza B., Mardiana, Sherly, Slaney, Clare Y., Johnstone, Ricky W., Trapani, Joseph A., Stagg, John, Loi, Sherene, Kats, Lev, Gyorki, David, Kershaw, Michael H., Darcy, Phillip K.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Clinical Investigation 2017
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330718/
https://ncbi.nlm.nih.gov/pubmed/28165340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI89455
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια