The Role of Inflammation in Regulating Platelet Production and Function: Toll-like Receptors in Platelets and Megakaryocytes

Por Beaulieu, Lea M., Freedman, Jane E.
Publicado em 2009

NFκB Regulation of Platelet Function: No Nucleus, No Genes, No Problem?

Por Beaulieu, Lea M., Freedman, Jane E.
Publicado em 2009

Activated protein C promotes breast cancer cell migration through interactions with EPCR and PAR-1

Por Beaulieu, Lea M., Church, Frank C.
Publicado em 2006

Innate Immunity and Toll-like Receptor Antagonists: A Potential Role in the Treatment of Cardiovascular Diseases

Por Lin, Elaine, Freedman, Jane E., Beaulieu, Lea M.
Publicado em 2009

Activated Protein C Enhances Cell Motility of Endothelial Cells and MDA-MB-231 Breast Cancer Cells by Intracellular Signal Transduction

Por Gramling, Mark W., Beaulieu, Lea M., Church, Frank C.
Publicado em 2009

Platelets and platelet-like particles mediate intercellular RNA transfer

Por Risitano, Antonina, Beaulieu, Lea M., Vitseva, Olga, Freedman, Jane E.
Publicado em 2012

Phosphatidylinositol 3-kinase/Akt regulates the balance between plasminogen activator inhibitor-1 and urokinase to promote migration of SKOV-3 ovarian cancer cells

Por Whitley, Brandi R., Beaulieu, Lea M., Carter, Jennifer C., Church, Frank C.
Publicado em 2006

Regulatory effects of TLR2 on megakaryocytic cell function

Por Beaulieu, Lea M., Lin, Elaine, Morin, Kristine M., Tanriverdi, Kahraman, Freedman, Jane E.
Publicado em 2011

M118, a novel low-molecular weight heparin with decreased polydispersity leads to enhanced anticoagulant activity and thrombotic occlusion in ApoE knockout mice

Por Chakrabarti, Subrata, Beaulieu, Lea M., Reyelt, Lara A., Iafrati, Mark D., Freedman, Jane E.
Publicado em 2009

Breast cancer and metabolic syndrome linked through the plasminogen activator inhibitor-1 cycle

Por Beaulieu, Lea M., Whitley, Brandi R., Wiesner, Theodore F., Rehault, Sophie M., Palmieri, Diane, Elkahloun, Abdel G., Church, Frank C.
Publicado em 2007

Stimulation of Toll-Like Receptor 2 in Human Platelets Induces a Thromboinflammatory Response Through Activation of Phosphoinositide 3-Kinase

Por Blair, Price, Rex, Sybille, Vitseva, Olga, Beaulieu, Lea, Tanriverdi, Kahraman, Chakrabarti, Subrata, Hayashi, Chie, Genco, Caroline A., Iafrati, Mark, Freedman, Jane E.
Publicado em 2008

Immune vs. thrombotic stimulation of platelets differentially regulates signaling pathways, intracellular protein-protein interactions, and α-granule release

Por Rex, Sybille, Beaulieu, Lea M., Perlman, David H., Vitseva, Olga, Blair, Price S., McComb, Mark E., Costello, Catherine E., Freedman, Jane E.
Publicado em 2009

Relationship Among Circulating Inflammatory Proteins, Platelet Gene Expression, and Cardiovascular Risk

Por McManus, David D., Beaulieu, Lea M., Mick, Eric, Tanriverdi, Kahraman, Larson, Martin G., Keaney, John F., Benjamin, Emelia J., Freedman, Jane E.
Publicado no Arterioscler Thromb Vasc Biol (2013)

Platelet-TLR7 mediates host survival and platelet count during viral infection in the absence of platelet-dependent thrombosis

Por Koupenova, Milka, Vitseva, Olga, MacKay, Christopher R., Beaulieu, Lea M., Benjamin, Emelia J., Mick, Eric, Kurt-Jones, Evelyn A., Ravid, Katya, Freedman, Jane E.
Publicado em 2014

Interleukin 1 Receptor 1 and Interleukin 1β Regulate Megakaryocyte Maturation, Platelet Activation, and Transcript Profile During Inflammation in Mice and Humans

Por Beaulieu, Lea M., Lin, Elaine, Mick, Eric, Koupenova, Milka, Weinberg, Ellen O., Kramer, Carolyn D., Genco, Caroline A., Tanriverdi, Kahraman, Larson, Martin G., Benjamin, Emelia J., Freedman, Jane E.
Publicado em 2014

Specific Inflammatory Stimuli Lead to Distinct Platelet Responses in Mice and Humans

Por Beaulieu, Lea M., Clancy, Lauren, Tanriverdi, Kahraman, Benjamin, Emelia J., Kramer, Carolyn D., Weinberg, Ellen O., He, Xianbao, Mekasha, Samrawit, Mick, Eric, Ingalls, Robin R., Genco, Caroline A., Freedman, Jane E.
Publicado no PLoS One (2015)

Caffeine and human DNA metabolism: the magic and the mystery

Por Kaufmann, William K., Heffernan, Timothy P., Beaulieu, Lea M., Doherty, Sharon, Frank, Alexandra R., Zhou, Yingchun, Bryant, Miriam F., Zhou, Tong, Luche, Douglas D., Nikolaishvili-Feinberg, Nana, Simpson, Dennis A., Cordeiro-Stone, Marila
Publicado em 2003

Distinct gene signatures in aortic tissue from ApoE(-/-) mice exposed to pathogens or Western diet

Por Kramer, Carolyn D, Weinberg, Ellen O, Gower, Adam C, He, Xianbao, Mekasha, Samrawit, Slocum, Connie, Beaulieu, Lea M, Wetzler, Lee, Alekseyev, Yuriy, Gibson, Frank C, Freedman, Jane E, Ingalls, Robin R, Genco, Caroline A
Publicado no BMC Genomics (2014)

Diverse human extracellular RNAs are widely detected in human plasma

Por Freedman, Jane E., Gerstein, Mark, Mick, Eric, Rozowsky, Joel, Levy, Daniel, Kitchen, Robert, Das, Saumya, Shah, Ravi, Danielson, Kirsty, Beaulieu, Lea, Navarro, Fabio C. P., Wang, Yaoyu, Galeev, Timur R., Holman, Alex, Kwong, Raymond Y., Murthy, Venkatesh, Tanriverdi, Selim E., Koupenova, Milka, Mikhalev, Ekaterina, Tanriverdi, Kahraman
Publicado no Nat Commun (2016)

Corrigendum: Diverse human extracellular RNAs are widely detected in human plasma

Por Freedman, Jane E., Gerstein, Mark, Mick, Eric, Rozowsky, Joel, Levy, Daniel, Kitchen, Robert, Das, Saumya, Shah, Ravi, Danielson, Kirsty, Beaulieu, Lea, Navarro, Fabio C. P., Wang, Yaoyu, Galeev, Timur R., Holman, Alex, Kwong, Raymond Y., Murthy, Venkatesh, Tanriverdi, Selim E., Koupenova, Milka, Mikhalev, Ekaterina, Tanriverdi, Kahraman
Publicado no Nat Commun (2016)