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Immune vs. thrombotic stimulation of platelets differentially regulates signaling pathways, intracellular protein-protein interactions, and α-granule release

In addition to hemostasis, platelets mediate inflammation and clearance of bacteria from the bloodstream. As with platelet-platelet interactions, platelet-bacteria interactions involve cytoskeletal rearrangements and release of granular content. Stimulation of the immune Toll-like receptor 2 (TLR2)...

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Detalhes bibliográficos
Main Authors: Rex, Sybille, Beaulieu, Lea M., Perlman, David H., Vitseva, Olga, Blair, Price S., McComb, Mark E., Costello, Catherine E., Freedman, Jane E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774228/
https://ncbi.nlm.nih.gov/pubmed/19572074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH08-08-0513
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