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Stimulation of Toll-Like Receptor 2 in Human Platelets Induces a Thromboinflammatory Response Through Activation of Phosphoinositide 3-Kinase

Cells of the innate immune system use Toll-like receptors (TLRs) to initiate the proinflammatory response to microbial infection. Recent studies have shown acute infections are associated with a transient increase in the risk of vascular thrombotic events. Although platelets play a central role in a...

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Detalhes bibliográficos
Main Authors: Blair, Price, Rex, Sybille, Vitseva, Olga, Beaulieu, Lea, Tanriverdi, Kahraman, Chakrabarti, Subrata, Hayashi, Chie, Genco, Caroline A., Iafrati, Mark, Freedman, Jane E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732983/
https://ncbi.nlm.nih.gov/pubmed/19106411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.185785
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