Platelet Toll-Like Receptors Mediate Thromboinflammatory Responses in Patients With Essential Thrombocythemia

Essential thrombocythemia (ET) is comprised among chronic myeloproliferative neoplasms (MPN) and is caused by driver mutations in JAK2, CALR, and MPL, which lead to megakaryocyte proliferation and prominent thrombocytosis. Thrombosis remains the main cause of morbidity in ET and is driven by the int...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Marín Oyarzún, Cecilia P., Glembotsky, Ana C., Goette, Nora P., Lev, Paola R., De Luca, Geraldine, Baroni Pietto, María C., Moiraghi, Beatriz, Castro Ríos, Miguel A., Vicente, Angeles, Marta, Rosana F., Schattner, Mirta, Heller, Paula G.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203216/
https://ncbi.nlm.nih.gov/pubmed/32425934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00705
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