Platelet Toll-Like Receptors Mediate Thromboinflammatory Responses in Patients With Essential Thrombocythemia

Essential thrombocythemia (ET) is comprised among chronic myeloproliferative neoplasms (MPN) and is caused by driver mutations in JAK2, CALR, and MPL, which lead to megakaryocyte proliferation and prominent thrombocytosis. Thrombosis remains the main cause of morbidity in ET and is driven by the int...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Marín Oyarzún, Cecilia P., Glembotsky, Ana C., Goette, Nora P., Lev, Paola R., De Luca, Geraldine, Baroni Pietto, María C., Moiraghi, Beatriz, Castro Ríos, Miguel A., Vicente, Angeles, Marta, Rosana F., Schattner, Mirta, Heller, Paula G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203216/
https://ncbi.nlm.nih.gov/pubmed/32425934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00705
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