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Platelet-TLR7 mediates host survival and platelet count during viral infection in the absence of platelet-dependent thrombosis
Viral infections have been associated with reduced platelet counts, the biological significance of which has remained elusive. Here, we show that infection with encephalomyocarditis virus (EMCV) rapidly reduces platelet count, and this response is attributed to platelet Toll-like receptor 7 (TLR7)....
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4118487/ https://ncbi.nlm.nih.gov/pubmed/24755410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-11-536003 |
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