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Activated Protein C Enhances Cell Motility of Endothelial Cells and MDA-MB-231 Breast Cancer Cells by Intracellular Signal Transduction

Activated protein C (APC), an anticoagulant serine protease, has been shown to have non-hemostatic functions related to inflammation, cell survival, and cell migration. In this study we investigate the mechanism by which APC promotes angiogenesis and breast cancer invasion using ex vivo and in vitro...

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Detalhes bibliográficos
Main Authors: Gramling, Mark W., Beaulieu, Lea M., Church, Frank C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812600/
https://ncbi.nlm.nih.gov/pubmed/19891966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2009.10.024
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