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Activated Protein C Enhances Cell Motility of Endothelial Cells and MDA-MB-231 Breast Cancer Cells by Intracellular Signal Transduction

Activated protein C (APC), an anticoagulant serine protease, has been shown to have non-hemostatic functions related to inflammation, cell survival, and cell migration. In this study we investigate the mechanism by which APC promotes angiogenesis and breast cancer invasion using ex vivo and in vitro...

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Bibliografische gegevens
Hoofdauteurs: Gramling, Mark W., Beaulieu, Lea M., Church, Frank C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812600/
https://ncbi.nlm.nih.gov/pubmed/19891966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2009.10.024
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