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Activated protein C promotes breast cancer cell migration through interactions with EPCR and PAR-1

Activated protein C (APC) is a serine protease that regulates thrombin (IIa) production through inactivation of blood coagulation factors Va and VIIIa. APC also has non-hemostatic functions related to inflammation, proliferation, and apoptosis through various mechanisms. Using two breast cancer cell...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Beaulieu, Lea M., Church, Frank C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055951/
https://ncbi.nlm.nih.gov/pubmed/17254565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2006.11.019
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