The genetic basis for inherited forms of sinoatrial dysfunction and atrioventricular node dysfunction

por Milanesi, Raffaella, Bucchi, Annalisa, Baruscotti, Mirko
Publicado no J Interv Card Electrophysiol (2015)

Current-dependent Block of Rabbit Sino-Atrial Node I(f) Channels by Ivabradine

por Bucchi, Annalisa, Baruscotti, Mirko, DiFrancesco, Dario
Publicado em 2002

Funny Current and Cardiac Rhythm: Insights from HCN Knockout and Transgenic Mouse Models

por Bucchi, Annalisa, Barbuti, Andrea, DiFrancesco, Dario, Baruscotti, Mirko
Publicado em 2012

Direct inhibition of the pacemaker (I(f)) current in rabbit sinoatrial node cells by genistein

por Altomare, Claudia, Tognati, Agnese, Bescond, Jocelyn, Ferroni, Arnaldo, Baruscotti, Mirko
Publicado em 2005

Effects of dronedarone on Acetylcholine-activated current in rabbit SAN cells

por Altomare, Claudia, Barbuti, Andrea, Viscomi, Carlo, Baruscotti, Mirko, DiFrancesco, Dario
Publicado em 2000

Coexistence of seizure episodes and symptomatic sinoatrial arrest occurring in two sisters suggests an underlying cardioneuronal channelopathy

por Carboni, Gian Piero, DiFrancesco, Jacopo C, Milanesi, Raffaella, Baruscotti, Mirko
Publicado em 2013

Integrated Allosteric Model of Voltage Gating of Hcn Channels

por Altomare, Claudia, Bucchi, Annalisa, Camatini, Eva, Baruscotti, Mirko, Viscomi, Carlo, Moroni, Anna, DiFrancesco, Dario
Publicado em 2001

Identification of the Molecular Site of Ivabradine Binding to HCN4 Channels

por Bucchi, Annalisa, Baruscotti, Mirko, Nardini, Marco, Barbuti, Andrea, Micheloni, Stefano, Bolognesi, Martino, DiFrancesco, Dario
Publicado em 2013

Age-Related Changes in Cardiac Autonomic Modulation and Heart Rate Variability in Mice

por Piantoni, Chiara, Carnevali, Luca, Molla, David, Barbuti, Andrea, DiFrancesco, Dario, Bucchi, Annalisa, Baruscotti, Mirko
Publicado no Front Neurosci (2021)

Screening and Identification of Cardioprotective Compounds From Wenxin Keli by Activity Index Approach and in vivo Zebrafish Model

por Liu, Hao, Chen, Xuechun, Zhao, Xiaoping, Zhao, Buchang, Qian, Ke, Shi, Yang, Baruscotti, Mirko, Wang, Yi
Publicado no Front Pharmacol (2018)

Heteromeric HCN1–HCN4 channels: a comparison with native pacemaker channels from the rabbit sinoatrial node

por Altomare, Claudia, Terragni, Benedetta, Brioschi, Chiara, Milanesi, Raffaella, Pagliuca, Cinzia, Viscomi, Carlo, Moroni, Anna, Baruscotti, Mirko, DiFrancesco, Dario
Publicado em 2003

A detailed characterization of the hyperpolarization-activated “funny” current (I(f)) in human-induced pluripotent stem cell (iPSC)–derived cardiomyocytes with pacemaker activity...

por Giannetti, Federica, Benzoni, Patrizia, Campostrini, Giulia, Milanesi, Raffaella, Bucchi, Annalisa, Baruscotti, Mirko, Dell’Era, Patrizia, Rossini, Alessandra, Barbuti, Andrea
Publicado no Pflugers Arch (2021)

I(NaP) selective inhibition reverts precocious inter- and motorneurons hyperexcitability in the Sod1-G93R zebrafish ALS model

por Benedetti, Lorena, Ghilardi, Anna, Rottoli, Elsa, De Maglie, Marcella, Prosperi, Laura, Perego, Carla, Baruscotti, Mirko, Bucchi, Annalisa, Del Giacco, Luca, Francolini, Maura
Publicado no Sci Rep (2016)

Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4

por Baruscotti, Mirko, Bucchi, Annalisa, Viscomi, Carlo, Mandelli, Giacomo, Consalez, Giacomo, Gnecchi-Rusconi, Tomaso, Montano, Nicola, Casali, Karina Rabello, Micheloni, Stefano, Barbuti, Andrea, DiFrancesco, Dario
Publicado em 2011

Recessive Loss-of-Function Mutation in the Pacemaker HCN2 Channel Causing Increased Neuronal Excitability in a Patient with Idiopathic Generalized Epilepsy

por DiFrancesco, Jacopo C., Barbuti, Andrea, Milanesi, Raffaella, Coco, Stefania, Bucchi, Annalisa, Bottelli, Georgia, Ferrarese, Carlo, Franceschetti, Silvana, Terragni, Benedetta, Baruscotti, Mirko, DiFrancesco, Dario
Publicado no J Neurosci (2011)

The expression of the rare caveolin-3 variant T78M alters cardiac ion channels function and membrane excitability

por Campostrini, Giulia, Bonzanni, Mattia, Lissoni, Alessio, Bazzini, Claudia, Milanesi, Raffaella, Vezzoli, Elena, Francolini, Maura, Baruscotti, Mirko, Bucchi, Annalisa, Rivolta, Ilaria, Fantini, Matteo, Severi, Stefano, Cappato, Riccardo, Crotti, Lia, J. Schwartz, Peter, DiFrancesco, Dario, Barbuti, Andrea
Publicado no Cardiovasc Res (2017)

A Loss-of-Function HCN4 Mutation Associated With Familial Benign Myoclonic Epilepsy in Infancy Causes Increased Neuronal Excitability

por Campostrini, Giulia, DiFrancesco, Jacopo C., Castellotti, Barbara, Milanesi, Raffaella, Gnecchi-Ruscone, Tomaso, Bonzanni, Mattia, Bucchi, Annalisa, Baruscotti, Mirko, Ferrarese, Carlo, Franceschetti, Silvana, Canafoglia, Laura, Ragona, Francesca, Freri, Elena, Labate, Angelo, Gambardella, Antonio, Costa, Cinzia, Gellera, Cinzia, Granata, Tiziana, Barbuti, Andrea, DiFrancesco, Dario
Publicado no Front Mol Neurosci (2018)

Human iPSC modelling of a familial form of atrial fibrillation reveals a gain of function of I(f) and I(CaL) in patient-derived cardiomyocytes

por Benzoni, Patrizia, Campostrini, Giulia, Landi, Sara, Bertini, Valeria, Marchina, Eleonora, Iascone, Maria, Ahlberg, Gustav, Olesen, Morten Salling, Crescini, Elisabetta, Mora, Cristina, Bisleri, Gianluigi, Muneretto, Claudio, Ronca, Roberto, Presta, Marco, Poliani, Pier Luigi, Piovani, Giovanna, Verardi, Rosanna, Di Pasquale, Elisa, Consiglio, Antonella, Raya, Angel, Torre, Eleonora, Lodrini, Alessandra Maria, Milanesi, Raffaella, Rocchetti, Marcella, Baruscotti, Mirko, DiFrancesco, Dario, Memo, Maurizio, Barbuti, Andrea, Dell’Era, Patrizia
Publicado no Cardiovasc Res (2020)

A circadian clock in the sinus node mediates day-night rhythms in Hcn4 and heart rate

por D’Souza, Alicia, Wang, Yanwen, Anderson, Cali, Bucchi, Annalisa, Baruscotti, Mirko, Olieslagers, Servé, Mesirca, Pietro, Johnsen, Anne Berit, Mastitskaya, Svetlana, Ni, Haibo, Zhang, Yu, Black, Nicholas, Cox, Charlotte, Wegner, Sven, Bano-Otalora, Beatriz, Petit, Cheryl, Gill, Eleanor, Logantha, Sunil Jit R.J., Dobrzynski, Halina, Ashton, Nick, Hart, George, Zhang, Rai, Zhang, Henggui, Cartwright, Elizabeth J., Wisloff, Ulrik, Mangoni, Matteo E., da Costa Martins, Paula A., Piggins, Hugh D., DiFrancesco, Dario, Boyett, Mark R.
Publicado no Heart Rhythm (2021)

Mammalian γ2 AMPK regulates intrinsic heart rate

por Yavari, Arash, Bellahcene, Mohamed, Bucchi, Annalisa, Sirenko, Syevda, Pinter, Katalin, Herring, Neil, Jung, Julia J., Tarasov, Kirill V., Sharpe, Emily J., Wolfien, Markus, Czibik, Gabor, Steeples, Violetta, Ghaffari, Sahar, Nguyen, Chinh, Stockenhuber, Alexander, Clair, Joshua R. St., Rimmbach, Christian, Okamoto, Yosuke, Yang, Dongmei, Wang, Mingyi, Ziman, Bruce D., Moen, Jack M., Riordon, Daniel R., Ramirez, Christopher, Paina, Manuel, Lee, Joonho, Zhang, Jing, Ahmet, Ismayil, Matt, Michael G., Tarasova, Yelena S., Baban, Dilair, Sahgal, Natasha, Lockstone, Helen, Puliyadi, Rathi, de Bono, Joseph, Siggs, Owen M., Gomes, John, Muskett, Hannah, Maguire, Mahon L., Beglov, Youlia, Kelly, Matthew, dos Santos, Pedro P. N., Bright, Nicola J., Woods, Angela, Gehmlich, Katja, Isackson, Henrik, Douglas, Gillian, Ferguson, David J. P., Schneider, Jürgen E., Tinker, Andrew, Wolkenhauer, Olaf, Channon, Keith M., Cornall, Richard J., Sternick, Eduardo B., Paterson, David J., Redwood, Charles S., Carling, David, Proenza, Catherine, David, Robert, Baruscotti, Mirko, DiFrancesco, Dario, Lakatta, Edward G., Watkins, Hugh, Ashrafian, Houman
Publicado no Nat Commun (2017)