Lens Connexins α3Cx46 and α8Cx50 Interact with Zonula Occludens Protein-1 (ZO-1)

por Nielsen, Peter A., Baruch, Amos, Shestopalov, Valery I., Giepmans, Ben N.G., Dunia, Irene, Benedetti, E. Lucio, Kumar, Nalin M.
Publicado em 2003

Preclinical pharmacokinetic characterization of an adipose tissue-targeting monoclonal antibody in obese and non-obese animals

por Rajan, Sharmila, Mandikian, Danielle, Baruch, Amos, Gelzleichter, Thomas R., Stevens, Dale, Sonoda, Junichiro, Cowan, Kyra, Boswell, C. Andrew, Stefanich, Eric
Publicado no MAbs (2017)

Modeling and Simulation to Support Phase 2 Dose Selection for RG7652, a Fully Human Monoclonal Antibody Against Proprotein Convertase Subtilisin/Kexin Type 9

por Budha, Nageshwar R., Leabman, Maya, Jin, Jin Y., Wada, D. Russell, Baruch, Amos, Peng, Kun, Tingley, Whittemore G., Davis, John D.
Publicado no AAPS J (2015)

Sustained activity of novel THIOMAB antibody-antibiotic conjugate against Staphylococcus aureus in a mouse model: Longitudinal pharmacodynamic assessment by bioluminescence imaging

por Zhou, Chenguang, Cai, Hao, Baruch, Amos, Lewin-Koh, Nicholas, Yang, Meng, Guo, Fengxun, Xu, Deming, Deng, Rong, Hazenbos, Wouter, Kamath, Amrita V.
Publicado no PLoS One (2019)

A major role for proteolytic activity and proteinase-activated receptor-2 in the pathogenesis of infectious colitis

por Hansen, Kristina K., Sherman, Philip M., Cellars, Laurie, Andrade-Gordon, Patricia, Pan, Zhengying, Baruch, Amos, Wallace, John L., Hollenberg, Morley D., Vergnolle, Nathalie
Publicado em 2005

Comparison of AMG 416 and cinacalcet in rodent models of uremia

por Walter, Sarah, Baruch, Amos, Alexander, Shawn T, Janes, Julie, Sho, Eiketsu, Dong, Jin, Yin, Qun, Maclean, Derek, Mendel, Dirk B, Karim, Felix, Johnson, Randolph M
Publicado em 2014

Prognostic Power of Pathogen Cell-Free DNA in Staphylococcus aureus Bacteremia

por Guimaraes, Alessander O, Gutierrez, Johnny, Maskarinec, Stacey A, Cao, Yi, Hong, Kyu, Ruffin, Felicia, Carrasco-Triguero, Montserrat, Peck, Melicent C, Fowler, Vance G, Baruch, Amos, Rosenberger, Carrie M
Publicado no Open Forum Infect Dis (2019)

Pharmacokinetics and pharmacodynamics of DSTA4637A: A novel THIOMAB™ antibody antibiotic conjugate against Staphylococcus aureus in mice

por Zhou, Chenguang, Lehar, Sophie, Gutierrez, Johnny, Rosenberger, Carrie M., Ljumanovic, Nina, Dinoso, Jason, Koppada, Neelima, Hong, Kyu, Baruch, Amos, Carrasco-Triguero, Montserrat, Saad, Ola, Mariathasan, Sanjeev, Kamath, Amrita V.
Publicado no MAbs (2016)

A phase 1 study to evaluate the safety and LDL cholesterol–lowering effects of RG7652, a fully human monoclonal antibody against proprotein convertase subtilisin/kexin type 9

por Baruch, Amos, Luca, Diana, Kahn, Robert S., Cowan, Kyra J., Leabman, Maya, Budha, Nageshwar R., Chiu, Cecilia P.C., Wu, Yan, Kirchhofer, Daniel, Peterson, Andrew, Davis Jr, John C., Tingley, Whittemore G.
Publicado no Clin Cardiol (2017)

Generation of ligand-receptor alliances by "SEA" module-mediated cleavage of membrane-associated mucin proteins

por Wreschner, Daniel H., McGuckin, Michael A., Williams, Stefanie J., Baruch, Amos, Yoeli, Merav, Ziv, Ravit, Okun, Liron, Zaretsky, Joseph, Smorodinsky, Nechama, Keydar, Iafa, Neophytou, Pavlos, Stacey, Martin, Lin, His-Hsien, Gordon, Siamon
Publicado em 2002

Amygdalar Activity Predicts Future Incident Diabetes Independently of Adiposity

por Osbome, Michael T., Ishai, Amorina, Hammad, Basma, Tung, Brian, Wang, Ying, Baruch, Amos, Fayad, Zahi A., Giles, Jon T., Lo, Janet, Shin, Lisa M., Grinspoon, Steven K., Koenen, Karestan C., Pitman, Roger K., Tawakol, Ahmed
Publicado no Psychoneuroendocrinology (2018)

Antibody-mediated activation of the FGFR1/Klothoβ complex corrects metabolic dysfunction and alters food preference in obese humans

por Baruch, Amos, Wong, Chin, Chinn, Leslie W., Vaze, Anjali, Sonoda, Junichiro, Gelzleichter, Thomas, Chen, Shan, Lewin-Koh, Nicholas, Morrow, Linda, Dheerendra, Suresh, Boismenu, Richard, Gutierrez, Johnny, Wakshull, Eric, Wilson, Maria E., Arora, Puneet S.
Publicado no Proc Natl Acad Sci U S A (2020)

1058. Prognostic Biomarkers for Persistent Bacteremia and Mortality in Complicated S. aureus Bloodstream Infection

por Cao, Yi, Guimaraes, Alessander, Hong, Kyu, Mayba, Oleg, Peck, Melicent, Gutierrez, Johnny, Ruffin, Felicia, Carrasco-Triguero, Montserrat, Dinoso, Jason, Clemenzi-Allen, A Asa, Koss, Catherine, Maskarinec, Stacey A, Chambers, Henry F, Fowler Jr., Vance G, Baruch, Amos, Rosenberger, Carrie
Publicado no Open Forum Infect Dis (2018)

Sustained Circulating Bacterial Deoxyribonucleic Acid Is Associated With Complicated Staphylococcus aureus Bacteremia

por Gutierrez, Johnny, Guimaraes, Alessander O, Lewin-Koh, Nicholas, Berhanu, Aklile, Xu, Min, Cao, Yi, Kim, Janice, Yan, Donghong, Chang, Joanna K, Dinoso, Jason B, Koss, Catherine A, Clemenzi-Allen, Angelo, Chambers, Henry F, Peck, Melicent C, Baruch, Amos, Rosenberger, Carrie M
Publicado no Open Forum Infect Dis (2019)

A Prognostic Model of Persistent Bacteremia and Mortality in Complicated Staphylococcus aureus Bloodstream Infection

por Guimaraes, Alessander O, Cao, Yi, Hong, Kyu, Mayba, Oleg, Peck, Melicent C, Gutierrez, Johnny, Ruffin, Felicia, Carrasco-Triguero, Montserrat, Dinoso, Jason B, Clemenzi-Allen, Angelo, Koss, Catherine A, Maskarinec, Stacey A, Chambers, Henry F, Fowler, Vance G, Baruch, Amos, Rosenberger, Carrie M
Publicado no Clin Infect Dis (2019)

Splenic Metabolic Activity Predicts Risk of Future Cardiovascular Events: Demonstration of a Cardiosplenic Axis in Humans

por Emami, Hamed, Singh, Parmanand, Macnabb, Megan, Vucic, Esad, Lavender, Zachary, Rudd, James H.F, Fayad, Zahi A, Lehrer-Graiwer, Joshua, Korsgren, Magnus, Figueroa, Amparo L, Fredrickson, Jill, Rubin, Barry, Hoffmann, Udo, Truong, Quynh A, Min, James K, Baruch, Amos, Nasir, Khurram, Nahrendorf, Matthias, Tawakol, Ahmed
Publicado no JACC Cardiovasc Imaging (2015)

Development of a therapeutic anti-HtrA1 antibody and the identification of DKK3 as a pharmacodynamic biomarker in geographic atrophy

por Tom, Irene, Pham, Victoria C., Katschke, Kenneth J., Li, Wei, Liang, Wei-Ching, Gutierrez, Johnny, Ah Young, Andrew, Figueroa, Isabel, Eshghi, Shadi Toghi, Lee, ChingWei V., Kanodia, Jitendra, Snipas, Scott J., Salvesen, Guy S., Lai, Phillip, Honigberg, Lee, van Lookeren Campagne, Menno, Kirchhofer, Daniel, Baruch, Amos, Lill, Jennie R.
Publicado no Proc Natl Acad Sci U S A (2020)

Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths

por Ruuth, Maija, Nguyen, Su Duy, Vihervaara, Terhi, Hilvo, Mika, Laajala, Teemu D, Kondadi, Pradeep Kumar, Gisterå, Anton, Lähteenmäki, Hanna, Kittilä, Tiia, Huusko, Jenni, Uusitupa, Matti, Schwab, Ursula, Savolainen, Markku J, Sinisalo, Juha, Lokki, Marja-Liisa, Nieminen, Markku S, Jula, Antti, Perola, Markus, Ylä-Herttula, Seppo, Rudel, Lawrence, Öörni, Anssi, Baumann, Marc, Baruch, Amos, Laaksonen, Reijo, Ketelhuth, Daniel F J, Aittokallio, Tero, Jauhiainen, Matti, Käkelä, Reijo, Borén, Jan, Williams, Kevin Jon, Kovanen, Petri T, Öörni, Katariina
Publicado no Eur Heart J (2018)

Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex

por Kolumam, Ganesh, Chen, Mark Z., Tong, Raymond, Zavala-Solorio, Jose, Kates, Lance, van Bruggen, Nicholas, Ross, Jed, Wyatt, Shelby K., Gandham, Vineela D., Carano, Richard A.D., Dunshee, Diana Ronai, Wu, Ai-Luen, Haley, Benjamin, Anderson, Keith, Warming, Søren, Rairdan, Xin Y., Lewin-Koh, Nicholas, Zhang, Yingnan, Gutierrez, Johnny, Baruch, Amos, Gelzleichter, Thomas R., Stevens, Dale, Rajan, Sharmila, Bainbridge, Travis W., Vernes, Jean-Michel, Meng, Y. Gloria, Ziai, James, Soriano, Robert H., Brauer, Matthew J., Chen, Yongmei, Stawicki, Scott, Kim, Hok Seon, Comps-Agrar, Laëtitia, Luis, Elizabeth, Spiess, Christoph, Wu, Yan, Ernst, James A., McGuinness, Owen P., Peterson, Andrew S., Sonoda, Junichiro
Publicado no EBioMedicine (2015)