Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths

AIMS: Low-density lipoprotein (LDL) particles cause atherosclerotic cardiovascular disease (ASCVD) through their retention, modification, and accumulation within the arterial intima. High plasma concentrations of LDL drive this disease, but LDL quality may also contribute. Here, we focused on the in...

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Detalhes bibliográficos
Publicado no:Eur Heart J
Main Authors: Ruuth, Maija, Nguyen, Su Duy, Vihervaara, Terhi, Hilvo, Mika, Laajala, Teemu D, Kondadi, Pradeep Kumar, Gisterå, Anton, Lähteenmäki, Hanna, Kittilä, Tiia, Huusko, Jenni, Uusitupa, Matti, Schwab, Ursula, Savolainen, Markku J, Sinisalo, Juha, Lokki, Marja-Liisa, Nieminen, Markku S, Jula, Antti, Perola, Markus, Ylä-Herttula, Seppo, Rudel, Lawrence, Öörni, Anssi, Baumann, Marc, Baruch, Amos, Laaksonen, Reijo, Ketelhuth, Daniel F J, Aittokallio, Tero, Jauhiainen, Matti, Käkelä, Reijo, Borén, Jan, Williams, Kevin Jon, Kovanen, Petri T, Öörni, Katariina
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047440/
https://ncbi.nlm.nih.gov/pubmed/29982602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehy319
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