Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths

AIMS: Low-density lipoprotein (LDL) particles cause atherosclerotic cardiovascular disease (ASCVD) through their retention, modification, and accumulation within the arterial intima. High plasma concentrations of LDL drive this disease, but LDL quality may also contribute. Here, we focused on the in...

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Publicat a:Eur Heart J
Autors principals: Ruuth, Maija, Nguyen, Su Duy, Vihervaara, Terhi, Hilvo, Mika, Laajala, Teemu D, Kondadi, Pradeep Kumar, Gisterå, Anton, Lähteenmäki, Hanna, Kittilä, Tiia, Huusko, Jenni, Uusitupa, Matti, Schwab, Ursula, Savolainen, Markku J, Sinisalo, Juha, Lokki, Marja-Liisa, Nieminen, Markku S, Jula, Antti, Perola, Markus, Ylä-Herttula, Seppo, Rudel, Lawrence, Öörni, Anssi, Baumann, Marc, Baruch, Amos, Laaksonen, Reijo, Ketelhuth, Daniel F J, Aittokallio, Tero, Jauhiainen, Matti, Käkelä, Reijo, Borén, Jan, Williams, Kevin Jon, Kovanen, Petri T, Öörni, Katariina
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Basic Science
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047440/
https://ncbi.nlm.nih.gov/pubmed/29982602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehy319
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