Streptococcus pneumoniae pneumolysin and neuraminidase A convert high-density lipoproteins into pro-atherogenic particles

High-density lipoproteins (HDLs) are a group of different subpopulations of sialylated particles that have an essential role in the reverse cholesterol transport (RCT) pathway. Importantly, changes in the protein and lipid composition of HDLs may lead to the formation of particles with reduced ather...

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Veröffentlicht in:iScience
Hauptverfasser: Syed, Shahan, Nissilä, Eija, Ruhanen, Hanna, Fudo, Satoshi, Gaytán, Meztlli O., Sihvo, Sanna P., Lorey, Martina B., Metso, Jari, Öörni, Katariina, King, Samantha J., Oommen, Oommen P., Jauhiainen, Matti, Meri, Seppo, Käkelä, Reijo, Haapasalo, Karita
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8175417/
https://ncbi.nlm.nih.gov/pubmed/34124613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102535
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