A Preclinical Population Pharmacokinetic Model for Anti‐CD20/CD3 T‐Cell‐Dependent Bispecific Antibodies

von Ferl, Gregory Z., Reyes, Arthur, Sun, Liping L., Cheu, Melissa, Oldendorp, Amy, Ramanujan, Saroja, Stefanich, Eric G.
Veröffentlicht in Clin Transl Sci (2018)

Mitigating the risk of cytokine release syndrome in a Phase I trial of CD20/CD3 bispecific antibody mosunetuzumab in NHL: impact of translational system modeling

von Hosseini, Iraj, Gadkar, Kapil, Stefanich, Eric, Li, Chi-Chung, Sun, Liping L., Chu, Yu-Waye, Ramanujan, Saroja
Veröffentlicht in NPJ Syst Biol Appl (2020)

Production, characterization and pharmacokinetic properties of antibodies with N-linked Mannose-5 glycans

von Yu, Marcella, Brown, Darren, Reed, Chae, Chung, Shan, Lutman, Jeff, Stefanich, Eric, Wong, Anne, Stephan, Jean-Philippe, Bayer, Robert
Veröffentlicht 2012

Preclinical pharmacokinetic characterization of an adipose tissue-targeting monoclonal antibody in obese and non-obese animals

von Rajan, Sharmila, Mandikian, Danielle, Baruch, Amos, Gelzleichter, Thomas R., Stevens, Dale, Sonoda, Junichiro, Cowan, Kyra, Boswell, C. Andrew, Stefanich, Eric
Veröffentlicht in MAbs (2017)

Role of the Distal Half of the c-Mpl Intracellular Domain in Control of Platelet Production by Thrombopoietin In Vivo

von Luoh, Shiuh-Ming, Stefanich, Eric, Solar, Gregg, Steinmetz, Hope, Lipari, Terry, Pestina, Tamara I., Jackson, Carl W., de Sauvage, Frederic J.
Veröffentlicht 2000

MTRX1011A, a humanized anti-CD4 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: a Phase I randomized, double-blind, placebo-controlled study incorporat...

von Scheerens, Heleen, Su, Zheng, Irving, Bryan, Townsend, Michael J, Zheng, Yanan, Stefanich, Eric, Chindalore, Vishala, Bingham, Clifton O, Davis, John C
Veröffentlicht 2011

Effect of antigen binding affinity and effector function on the pharmacokinetics and pharmacodynamics of anti-IgE monoclonal antibodies

von Mortensen, Deborah L., Prabhu, Saileta, Stefanich, Eric G., Kadkhodayan-Fischer, Saloumeh, Gelzleichter, Thomas R., Baker, Dana, Jiang, Jenny, Wallace, Kristin, Iyer, Suhasini, Fielder, Paul J., Putnam, Wendy S.
Veröffentlicht 2012

An integrated approach for characterizing immunogenic responses toward a bispecific antibody

von Cohen, Sivan, Chung, Shan, Spiess, Christoph, Lundin, Victor, Stefanich, Eric, Laing, Steven T., Clark, Vanessa, Brumm, Jochen, Zhou, Ying, Huang, Catherine, Guerrero, Joyce, Myneni, Srividya, Yadav, Rajbharan, Siradze, Ketevan, Peng, Kun
Veröffentlicht in MAbs (2021)

Nonclinical safety assessment of a human interleukin‐22FC IG fusion protein demonstrates in vitro to in vivo and cross‐species translatability

von Lee, Donna W., Zhong, Shelly, Pai, Rama, Rae, Julie, Sukumaran, Siddharth, Stefanich, Eric G., Lutman, Jeff, Doudement, Estelle, Wang, Xiaoting, Harder, Brandon, Lekkerkerker, Annemarie, Herman, Ann, Ouyang, Wenjun, Danilenko, Dimitry M.
Veröffentlicht in Pharmacol Res Perspect (2018)

Development of a Human IgG4 Bispecific Antibody for Dual Targeting of Interleukin-4 (IL-4) and Interleukin-13 (IL-13) Cytokines

von Spiess, Christoph, Bevers, Jack, Jackman, Janet, Chiang, Nancy, Nakamura, Gerald, Dillon, Michael, Liu, Hongbin, Molina, Patricia, Elliott, J. Michael, Shatz, Whitney, Scheer, Justin M., Giese, Glen, Persson, Josefine, Zhang, Yin, Dennis, Mark S., Giulianotti, James, Gupta, Prateek, Reilly, Dorothea, Palma, Enzo, Wang, Jianyong, Stefanich, Eric, Scheerens, Heleen, Fuh, Germaine, Wu, Lawren C.
Veröffentlicht 2013

Functional Consequences of the Macrophage Stimulating Protein 689C Inflammatory Bowel Disease Risk Allele

von Kauder, Steven E., Santell, Lydia, Mai, Elaine, Wright, Lilyan Y., Luis, Elizabeth, N'Diaye, Elsa N., Lutman, Jeff, Ratti, Navneet, Sa, Susan M., Maun, Henry R., Stefanich, Eric, Gonzalez, Lino C., Graham, Robert R., Diehl, Lauri, Faubion, William A., Keir, Mary E., Young, Judy, Chaudhuri, Amitabha, Lazarus, Robert A., Egen, Jackson G.
Veröffentlicht 2013