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Role of the Distal Half of the c-Mpl Intracellular Domain in Control of Platelet Production by Thrombopoietin In Vivo

The cytokine thrombopoietin (TPO) controls the formation of megakaryocytes and platelets from hematopoietic stem cells. TPO exerts its effect through activation of the c-Mpl receptor and of multiple downstream signal transduction pathways. While the membrane-proximal half of the cytoplasmic domain a...

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Detaylı Bibliyografya
Asıl Yazarlar: Luoh, Shiuh-Ming, Stefanich, Eric, Solar, Gregg, Steinmetz, Hope, Lipari, Terry, Pestina, Tamara I., Jackson, Carl W., de Sauvage, Frederic J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2000
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC85116/
https://ncbi.nlm.nih.gov/pubmed/10611229
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