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Ubiquitination and degradation of the thrombopoietin receptor c-Mpl
Regulation of growth factor and cytokine signaling is essential for maintaining physiologic numbers of circulating hematopoietic cells. Thrombopoietin (Tpo), acting through its receptor c-Mpl, is required for hematopoietic stem cell maintenance and megakaryopoiesis. Therefore, the negative regulatio...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2826235/ https://ncbi.nlm.nih.gov/pubmed/19880496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-06-227033 |
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