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YRRL motifs in the cytoplasmic domain of the thrombopoietin receptor regulate receptor internalization and degradation

Thrombopoietin (Tpo), acting through the c-Mpl receptor, promotes the survival and proliferation of hematopoietic stem and progenitor cells and drives megakaryocyte differentiation. The proproliferation and survival signals activated by Tpo must therefore be tightly regulated to prevent uncontrolled...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Hitchcock, Ian S., Chen, Maximus M., King, Jennifer R., Kaushansky, Kenneth
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Hematology 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532800/
https://ncbi.nlm.nih.gov/pubmed/18487512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-01-134049
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