טוען...
An amphipathic motif at the transmembrane-cytoplasmic junction prevents autonomous activation of the thrombopoietin receptor
Ligand binding to the thrombopoietin receptor (TpoR) is thought to impose a dimeric receptor conformation(s) leading to hematopoietic stem cell renewal, megakaryocyte differentiation, and platelet formation. Unlike other cytokine receptors, such as the erythropoietin receptor, TpoR contains an amphi...
שמור ב:
| Main Authors: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
© 2006 by The American Society of Hematology
2006
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1379661/ https://ncbi.nlm.nih.gov/pubmed/16249382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2600 |
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