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Dissecting the thrombopoietin receptor: Functional elements of the Mpl cytoplasmic domain

Thrombopoietin (TPO) acts through its receptor, Mpl, to stimulate the proliferation and maturation of megakaryocytes and their progenitors. The Mpl cytoplasmic domain controls this process through assembly of an active signaling complex using various receptor docking sites. In this report, eight car...

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Detalhes bibliográficos
Main Authors: Drachman, Jonathan G., Kaushansky, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20091/
https://ncbi.nlm.nih.gov/pubmed/9122198
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