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Icaritin Provokes Serum Thrombopoietin and Downregulates Thrombopoietin/MPL of the Bone Marrow in a Mouse Model of Immune Thrombocytopenia

Immune thrombocytopenia (ITP) is a common acquired autoimmune disease, and thrombopoietin (TPO) is an important cytokine that regulates the production of megakaryocytes and platelets. We have identified a biologically active component, icaritin, from a Chinese herba epimedii extract. Icaritin promot...

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Bibliografische Detailangaben
Hauptverfasser: Ke Zhang, Zhenfeng Dai, Runzhe Liu, Fang Tian, Xi Liu, Yi Sun, Xin Zhao, Xiaoping Pu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley 2018-01-01
Schriftenreihe:Mediators of Inflammation
Online-Zugang:http://dx.doi.org/10.1155/2018/7235639
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