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Phosphorylated c-MPL tyrosine 591 regulates thrombopoietin-induced signaling
Thrombopoietin (TPO) is the primary regulator of platelet production, affecting cell survival, proliferation and differentiation through binding to and stimulation of the cell surface receptor c-MPL. Activating mutations in c-MPL constitutively stimulate downstream signaling pathways, leading to abe...
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| Pubblicato in: | Exp Hematol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5802363/ https://ncbi.nlm.nih.gov/pubmed/24607955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2014.02.007 |
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