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The thrombopoietin receptor: revisiting the master regulator of platelet production

Thrombopoietin (TPO) and its receptor, MPL, are the primary regulators of platelet production and critical for hematopoietic stem cell (HSC) maintenance. Since TPO was first cloned in 1994, the physiological and pathological roles of TPO and MPL have been well characterized, culminating in the first...

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Bibliografski detalji
Izdano u:Platelets
Glavni autori: Hitchcock, Ian S., Hafer, Maximillian, Sangkhae, Veena, Tucker, Julie A.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8292222/
https://ncbi.nlm.nih.gov/pubmed/34097561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09537104.2021.1925102
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