A major role for proteolytic activity and proteinase-activated receptor-2 in the pathogenesis of infectious colitis

Citrobacter rodentium is a bacterial pathogen that causes a murine infectious colitis equivalent to enterohemorrhagic Escherichia coli infection in humans. Colonic luminal fluid from C. rodentium-infected mice, but not from sham-infected mice, contains active serine proteinases that can activate pro...

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Detalhes bibliográficos
Main Authors: Hansen, Kristina K., Sherman, Philip M., Cellars, Laurie, Andrade-Gordon, Patricia, Pan, Zhengying, Baruch, Amos, Wallace, John L., Hollenberg, Morley D., Vergnolle, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149409/
https://ncbi.nlm.nih.gov/pubmed/15919826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409535102
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