Proteinase-activated receptor 2 is an anti-inflammatory signal for colonic lamina propria lymphocytes in a mouse model of colitis

The proteinase-activated receptor 2 (PAR-2) is a member of a family of G protein-coupled receptors for proteases. Proteases cleave PARs within the extracellular N-terminal domains to expose tethered ligands that bind to and activate the cleaved receptors. PAR-2 is highly expressed in colon in epithe...

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Detalhes bibliográficos
Main Authors: Fiorucci, Stefano, Mencarelli, Andrea, Palazzetti, Barbara, Distrutti, Eleonora, Vergnolle, Nathalie, Hollenberg, Morley D., Wallace, John L., Morelli, Antonio, Cirino, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC61145/
https://ncbi.nlm.nih.gov/pubmed/11717450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.241377298
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