A role for proteinase-activated receptor–1 in inflammatory bowel diseases

Proteinase-activated receptor–1 (PAR(1)), a G protein–coupled receptor activated by thrombin, is highly expressed in different cell types of the gastrointestinal tract. The activity of thrombin and of other proteinases is significantly increased in the colon of inflammatory bowel disease (IBD) patie...

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Detalhes bibliográficos
Main Authors: Vergnolle, Nathalie, Cellars, Laurie, Mencarelli, Andrea, Rizzo, Giovanni, Swaminathan, Sunita, Beck, Paul, Steinhoff, Martin, Andrade-Gordon, Patricia, Bunnett, Nigel W., Hollenberg, Morley D., Wallace, John L., Cirino, Giuseppe, Fiorucci, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC526028/
https://ncbi.nlm.nih.gov/pubmed/15545995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421689
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