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A role for proteinase-activated receptor–1 in inflammatory bowel diseases
Proteinase-activated receptor–1 (PAR(1)), a G protein–coupled receptor activated by thrombin, is highly expressed in different cell types of the gastrointestinal tract. The activity of thrombin and of other proteinases is significantly increased in the colon of inflammatory bowel disease (IBD) patie...
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| Główni autorzy: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Clinical Investigation
2004
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC526028/ https://ncbi.nlm.nih.gov/pubmed/15545995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421689 |
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