Macrophages: Master Regulators of Inflammation and Fibrosis

Por Wynn, Thomas A., Barron, Luke
Publicado em 2010

Fibrosis is regulated by Th2 and Th17 responses and by dynamic interactions between fibroblasts and macrophages

Por Barron, Luke, Wynn, Thomas A.
Publicado em 2011

Macrophage activation governs schistosomiasis-induced inflammation and fibrosis

Por Barron, Luke, Wynn, Thomas A.
Publicado em 2011

Lung Pericytes and Resident Fibroblasts: Busy Multitaskers

Por Barron, Luke, Gharib, Sina A., Duffield, Jeremy S.
Publicado no Am J Pathol (2016)

Cooperative Roles of CTLA-4 and Regulatory T Cells in Tolerance to an Islet Cell Antigen

Por Eggena, Mark P., Walker, Lucy S.K., Nagabhushanam, Vijaya, Barron, Luke, Chodos, Anna, Abbas, Abul K.
Publicado em 2004

Mechanisms of IL-2–dependent maintenance of functional regulatory T cells

Por Barron, Luke, Dooms, Hans, Hoyer, Katrina K., Kuswanto, Wilson, Hofmann, Jerry, O’Gorman, William E., Abbas, Abul K.
Publicado em 2010

Quantitative Assessment of Macrophage Functions in Repair and Fibrosis

Por Wynn, Thomas A., Barron, Luke, Thompson, Robert W., Madala, Satish K., Wilson, Mark S., Cheever, Allen W., Ramalingam, Thirumalai
Publicado em 2011

Melanoma-initiating cells exploit M2 macrophage TGFβ and arginase pathway for survival and proliferation

Por Tham, Muly, Tan, Kar Wai, Keeble, Jo, Wang, Xiaojie, Hubert, Sandra, Barron, Luke, Tan, Nguan Soon, Kato, Masashi, Prevost-Blondel, Armelle, Angeli, Veronique, Abastado, Jean-Pierre
Publicado no Oncotarget (2014)

Pentraxin-2 suppresses c-Jun/AP-1 signaling to inhibit progressive fibrotic disease

Por Nakagawa, Naoki, Barron, Luke, Gomez, Ivan G., Johnson, Bryce G., Roach, Allie M., Kameoka, Sei, Jack, Richard M., Lupher, Mark L., Gharib, Sina A., Duffield, Jeremy S.
Publicado no JCI Insight (2016)

Role of Arginase 1 from Myeloid Cells in Th2-Dominated Lung Inflammation

Por Barron, Luke, Smith, Amber M., El Kasmi, Karim C., Qualls, Joseph E., Huang, Xiaozhu, Cheever, Allen, Borthwick, Lee A., Wilson, Mark S., Murray, Peter J., Wynn, Thomas A.
Publicado em 2013

The transcription factor GATA3 is critical for the development of all IL-7Rα-expressing innate lymphoid cells

Por Yagi, Ryoji, Zhong, Chao, Northrup, Daniel L., Yu, Fang, Bouladoux, Nicolas, Spencer, Sean, Hu, Gangqing, Barron, Luke, Sharma, Suveena, Nakayama, Toshinori, Belkaid, Yasmine, Zhao, Keji, Zhu, Jinfang
Publicado em 2014

Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis

Por Borthwick, Lee A., Barron, Luke, Hart, Kevin M., Vannella, Kevin M., Thompson, Robert W., Oland, Sandra, Cheever, Allen, Sciurba, Joshua, Ramalingam, Thirumalai R., Fisher, Andrew J., Wynn, Thomas A.
Publicado no Mucosal Immunol (2015)

Muc5ac: a critical component mediating the rejection of enteric nematodes

Por Hasnain, Sumaira Z., Evans, Christopher M., Roy, Michelle, Gallagher, Amanda L., Kindrachuk, Kristen N., Barron, Luke, Dickey, Burton F., Wilson, Mark S., Wynn, Thomas A., Grencis, Richard K., Thornton, David J.
Publicado em 2011

Incomplete Deletion of IL-4Rα by LysM(Cre) Reveals Distinct Subsets of M2 Macrophages Controlling Inflammation and Fibrosis in Chronic Schistosomiasis

Por Vannella, Kevin M., Barron, Luke, Borthwick, Lee A., Kindrachuk, Kristen N., Narasimhan, Prakash Babu, Hart, Kevin M., Thompson, Robert W., White, Sandra, Cheever, Allen W., Ramalingam, Thirumalai R., Wynn, Thomas A.
Publicado em 2014

T Cells Encountering Myeloid Cells Programmed for Amino Acid-dependent Immunosuppression Use Rictor/mTORC2 Protein for Proliferative Checkpoint Decisions

Por Van de Velde, Lee-Ann, Subramanian, Chitra, Smith, Amber M., Barron, Luke, Qualls, Joseph E., Neale, Geoffrey, Alfonso-Pecchio, Adolfo, Jackowski, Suzanne, Rock, Charles O., Wynn, Thomas A., Murray, Peter J.
Publicado no J Biol Chem (2017)

The TNF-Family Cytokine TL1A Promotes Allergic Immunopathology through Group 2 Innate Lymphoid Cells

Por Meylan, Françoise, Hawley, Eric T., Barron, Luke, Barlow, Jillian L., Penumetcha, Pallavi, Pelletier, Martin, Sciumè, Giuseppe, Richard, Arianne C., Hayes, Erika T., Gomez-Rodriguez, Julio, Chen, Xi, Paul, William E., Wynn, Thomas A., McKenzie, Andrew N.J., Siegel, Richard M.
Publicado em 2013

Acidic chitinase primes the protective immune response to gastrointestinal nematodes

Por Vannella, Kevin M, Ramalingam, Thirumalai R, Hart, Kevin M, de Queiroz Prado, Rafael, Sciurba, Joshua, Barron, Luke, Borthwick, Lee A, Smith, Allen D, Mentink-Kane, Margaret, White, Sandra, Thompson, Robert W, Cheever, Allen W, Bock, Kevin, Moore, Ian, Fitz, Lori J, Urban, Joseph F, Wynn, Thomas A
Publicado no Nat Immunol (2016)

A Trypanosoma brucei Kinesin Heavy Chain Promotes Parasite Growth by Triggering Host Arginase Activity

Por De Muylder, Géraldine, Daulouède, Sylvie, Lecordier, Laurence, Uzureau, Pierrick, Morias, Yannick, Van Den Abbeele, Jan, Caljon, Guy, Hérin, Michel, Holzmuller, Philippe, Semballa, Silla, Courtois, Pierrette, Vanhamme, Luc, Stijlemans, Benoît, De Baetselier, Patrick, Barrett, Michael P., Barlow, Jillian L., McKenzie, Andrew N. J., Barron, Luke, Wynn, Thomas A., Beschin, Alain, Vincendeau, Philippe, Pays, Etienne
Publicado em 2013