Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis

The roles of macrophages in type 2-driven inflammation and fibrosis remain unclear. Here, using CD11b-Diphtheria Toxin Receptor (DTR) transgenic mice and three models of IL-13-dependent inflammation, fibrosis, and immunity, we show that CD11b(+) F4/80(+) Ly6C+ macrophages are required for the mainte...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Mucosal Immunol
Autors principals: Borthwick, Lee A., Barron, Luke, Hart, Kevin M., Vannella, Kevin M., Thompson, Robert W., Oland, Sandra, Cheever, Allen, Sciurba, Joshua, Ramalingam, Thirumalai R., Fisher, Andrew J., Wynn, Thomas A.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626445/
https://ncbi.nlm.nih.gov/pubmed/25921340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2015.34
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars