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Fibrosis is regulated by Th2 and Th17 responses and by dynamic interactions between fibroblasts and macrophages

Dysregulated wound healing leads to fibrosis, whereby fibroblasts synthesize excess extracellular matrix and scarring impairs proper organ function. Although fibrotic diseases arise from diverse causes and display heterogeneous features, fibrosis commonly associates with chronic inflammation. Recent...

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Detalhes bibliográficos
Main Authors: Barron, Luke, Wynn, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302189/
https://ncbi.nlm.nih.gov/pubmed/21292997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00414.2010
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