Endoplasmic reticulum and oxidative stress in immunopathology: understanding the crosstalk between cellular stress and inflammation

Por Hasnain, Sumaira Z
Publicado no Clin Transl Immunology (2018)

Immune regulation of the unfolded protein response at the mucosal barrier in viral infection

Por Wang, Ran, Moniruzzaman, Md., Shuffle, Eric, Lourie, Rohan, Hasnain, Sumaira Z
Publicado no Clin Transl Immunology (2018)

Serine Protease(s) Secreted by the Nematode Trichuris muris Degrade the Mucus Barrier

Por Hasnain, Sumaira Z., McGuckin, Michael A., Grencis, Richard K., Thornton, David J.
Publicado em 2012

Interleukin (IL)-22 from IL-20 Subfamily of Cytokines Induces Colonic Epithelial Cell Proliferation Predominantly through ERK1/2 Pathway

Por Moniruzzaman, Md., Wang, Ran, Jeet, Varinder, McGuckin, Michael A., Hasnain, Sumaira Z.
Publicado no Int J Mol Sci (2019)

The interplay between endoplasmic reticulum stress and inflammation

Por Hasnain, Sumaira Z, Lourie, Rohan, Das, Indrajit, Chen, Alice C‐H, McGuckin, Michael A
Publicado no Immunol Cell Biol (2012)

The effect of interleukin-22 treatment on autoimmune diabetes in the NOD mouse

Por Borg, Danielle J., Wang, Ran, Murray, Lydia, Tong, Hui, Steptoe, Raymond J., McGuckin, Michael A., Hasnain, Sumaira Z.
Publicado no Diabetologia (2017)

Immune-driven alterations in mucin sulphation is an important mediator of Trichuris muris helminth expulsion

Por Hasnain, Sumaira Z., Dawson, Paul A., Lourie, Rohan, Hutson, Peter, Tong, Hui, Grencis, Richard K., McGuckin, Michael A., Thornton, David J.
Publicado no PLoS Pathog (2017)

Mucin Gene Deficiency in Mice Impairs Host Resistance to an Enteric Parasitic Infection

Por Hasnain, Sumaira Z., Wang, Huaqing, Ghia, Jean–Eric, Haq, Nihal, Deng, Yikang, Velcich, Anna, Grencis, Richard K., Thornton, David J., Khan, Waliul I.
Publicado em 2010

Fibre Intake Is Independently Associated with Increased Circulating Interleukin-22 in Individuals with Metabolic Syndrome

Por Torquati, Luciana, Coombes, Jeff S., Murray, Lydia, Hasnain, Sumaira Z., Mallard, Alistair R., McGuckin, Michael A., Fassett, Robert G., Croci, Ilaria, Ramos, Joyce S.
Publicado no Nutrients (2019)

Influence of the MUC1 Cell Surface Mucin on Gastric Mucosal Gene Expression Profiles in Response to Helicobacter pylori Infection in Mice

Por Sheng, Yong H., Ng, Garrett Z., Summers, Kim M., Every, Alison L., Price, Gareth, Hasnain, Sumaira Z., Sutton, Philip, McGuckin, Michael A.
Publicado no Front Cell Infect Microbiol (2020)

Rationally Designed Dendritic Silica Nanoparticles for Oral Delivery of Exenatide

Por Abeer, Muhammad Mustafa, Meka, Anand Kumar, Pujara, Naisarg, Kumeria, Tushar, Strounina, Ekaterina, Nunes, Rute, Costa, Ana, Sarmento, Bruno, Hasnain, Sumaira Z., Ross, Benjamin P., Popat, Amirali
Publicado no Pharmaceutics (2019)

Adult Non-Cystic Fibrosis Bronchiectasis Is Characterised by Airway Luminal Th17 Pathway Activation

Por Chen, Alice C.-H., Martin, Megan L., Lourie, Rohan, Rogers, Geraint B., Burr, Lucy D., Hasnain, Sumaira Z., Bowler, Simon D., McGuckin, Michael A., Serisier, David J.
Publicado no PLoS One (2015)

Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins

Por Das, Indrajit, Png, Chin Wen, Oancea, Iulia, Hasnain, Sumaira Z., Lourie, Rohan, Proctor, Martina, Eri, Rajaraman D., Sheng, Yong, Crane, Denis I., Florin, Timothy H., McGuckin, Michael A.
Publicado em 2013

PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa

Por Burr, Lucy D., Rogers, Geraint B., Chen, Alice C-H, Taylor, Steven L., Bowler, Simon D., Keating, Rebecca L., Martin, Megan L., Hasnain, Sumaira Z., McGuckin, Michael A.
Publicado no PLoS One (2018)

Effect of Different Volumes of Interval Training and Continuous Exercise on Interleukin-22 in Adults with Metabolic Syndrome: A Randomized Trial

Por Ramos, Joyce S, Dalleck, Lance C, Stennett, Rebecca C, Mielke, Gregore I, Keating, Shelley E, Murray, Lydia, Hasnain, Sumaira Z, Fassett, Robert G, McGuckin, Michael, Croci, Ilaria, Coombes, Jeff S
Publicado no Diabetes Metab Syndr Obes (2020)

Muc5ac: a critical component mediating the rejection of enteric nematodes

Por Hasnain, Sumaira Z., Evans, Christopher M., Roy, Michelle, Gallagher, Amanda L., Kindrachuk, Kristen N., Barron, Luke, Dickey, Burton F., Wilson, Mark S., Wynn, Thomas A., Grencis, Richard K., Thornton, David J.
Publicado em 2011

Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction

Por Borg, Danielle J., Yap, Felicia Y. T., Keshvari, Sahar, Simmons, David G., Gallo, Linda A., Fotheringham, Amelia K., Zhuang, Aowen, Slattery, Robyn M., Hasnain, Sumaira Z., Coughlan, Melinda T., Kantharidis, Phillip, Forbes, Josephine M.
Publicado no Islets (2017)

High glucose levels increase influenza-associated damage to the pulmonary epithelial-endothelial barrier

Por Hulme, Katina D, Yan, Limin, Marshall, Rebecca J, Bloxham, Conor J, Upton, Kyle R, Hasnain, Sumaira Z, Bielefeldt-Ohmann, Helle, Loh, Zhixuan, Ronacher, Katharina, Chew, Keng Yih, Gallo, Linda A, Short, Kirsty R
Publicado no eLife (2020)

High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22

Por Gulhane, Max, Murray, Lydia, Lourie, Rohan, Tong, Hui, Sheng, Yong H., Wang, Ran, Kang, Alicia, Schreiber, Veronika, Wong, Kuan Yau, Magor, Graham, Denman, Stuart, Begun, Jakob, Florin, Timothy H., Perkins, Andrew, Cuív, Páraic Ó., McGuckin, Michael A., Hasnain, Sumaira Z.
Publicado no Sci Rep (2016)

Acute graft-versus-host disease is regulated by an IL-17–sensitive microbiome

Por Varelias, Antiopi, Ormerod, Kate L., Bunting, Mark D., Koyama, Motoko, Gartlan, Kate H., Kuns, Rachel D., Lachner, Nancy, Locke, Kelly R., Lim, Chun Y., Henden, Andrea S., Zhang, Ping, Clouston, Andrew D., Hasnain, Sumaira Z., McGuckin, Michael A., Blazar, Bruce R., MacDonald, Kelli P. A., Hugenholtz, Philip, Hill, Geoffrey R.
Publicado no Blood (2017)