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Acute graft-versus-host disease is regulated by an IL-17–sensitive microbiome
Donor T-cell–derived interleukin-17A (IL-17A) can mediate late immunopathology in graft-versus-host disease (GVHD), however protective roles remain unclear. Using multiple cytokine and cytokine receptor subunit knockout mice, we demonstrate that stem cell transplant recipients lacking the ability to...
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| 出版年: | Blood |
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| 主要な著者: | , , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5391622/ https://ncbi.nlm.nih.gov/pubmed/28137828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-08-732628 |
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