GVHD prevents NK-cell–dependent leukemia and virus-specific innate immunity

Allogeneic bone marrow transplantation (allo-BMT) is a curative therapy for hematological malignancies, but is associated with significant complications, principally graft-versus-host disease (GVHD) and opportunistic infections. Natural killer (NK) cells mediate important innate immunity that provid...

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Udgivet i:Blood
Main Authors: Bunting, Mark D., Varelias, Antiopi, Souza-Fonseca-Guimaraes, Fernando, Schuster, Iona S., Lineburg, Katie E., Kuns, Rachel D., Fleming, Peter, Locke, Kelly R., Huntington, Nicholas D., Blazar, Bruce R., Lane, Steven W., Tey, Siok-Keen, MacDonald, Kelli P. A., Smyth, Mark J., Degli-Esposti, Mariapia A., Hill, Geoffrey R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2017
Fag:
Transplantation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290987/
https://ncbi.nlm.nih.gov/pubmed/27927647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-08-734020
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