Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHD

Chronic graft-versus-host disease (cGVHD) is a major cause of late mortality following allogeneic bone marrow transplantation (BMT) and is characterized by tissue fibrosis manifesting as scleroderma and bronchiolitis obliterans. The development of acute GVHD (aGVHD) is a powerful clinical predictor...

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Detalhes bibliográficos
Publicado no:Blood
Principais autores: Leveque-El mouttie, Lucie, Koyama, Motoko, Le Texier, Laetitia, Markey, Kate A., Cheong, Melody, Kuns, Rachel D., Lineburg, Katie E., Teal, Bianca E., Alexander, Kylie A., Clouston, Andrew D., Blazar, Bruce R., Hill, Geoffrey R., MacDonald, Kelli P. A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982453/
https://ncbi.nlm.nih.gov/pubmed/27338097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-11-680876
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