CSF-1–dependant donor-derived macrophages mediate chronic graft-versus-host disease

Chronic GVHD (cGVHD) is the major cause of late, nonrelapse death following stem cell transplantation and characteristically develops in organs such as skin and lung. Here, we used multiple murine models of cGVHD to investigate the contribution of macrophage populations in the development of cGVHD....

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Main Authors: Alexander, Kylie A., Flynn, Ryan, Lineburg, Katie E., Kuns, Rachel D., Teal, Bianca E., Olver, Stuart D., Lor, Mary, Raffelt, Neil C., Koyama, Motoko, Leveque, Lucie, Le Texier, Laetitia, Melino, Michelle, Markey, Kate A., Varelias, Antiopi, Engwerda, Christian, Serody, Jonathan S., Janela, Baptiste, Ginhoux, Florent, Clouston, Andrew D., Blazar, Bruce R., Hill, Geoffrey R., MacDonald, Kelli P.A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191032/
https://ncbi.nlm.nih.gov/pubmed/25157821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75935
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