CSF-1–dependant donor-derived macrophages mediate chronic graft-versus-host disease

Chronic GVHD (cGVHD) is the major cause of late, nonrelapse death following stem cell transplantation and characteristically develops in organs such as skin and lung. Here, we used multiple murine models of cGVHD to investigate the contribution of macrophage populations in the development of cGVHD....

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Bibliographic Details
Main Authors: Alexander, Kylie A., Flynn, Ryan, Lineburg, Katie E., Kuns, Rachel D., Teal, Bianca E., Olver, Stuart D., Lor, Mary, Raffelt, Neil C., Koyama, Motoko, Leveque, Lucie, Le Texier, Laetitia, Melino, Michelle, Markey, Kate A., Varelias, Antiopi, Engwerda, Christian, Serody, Jonathan S., Janela, Baptiste, Ginhoux, Florent, Clouston, Andrew D., Blazar, Bruce R., Hill, Geoffrey R., MacDonald, Kelli P.A.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191032/
https://ncbi.nlm.nih.gov/pubmed/25157821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75935
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