Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host disease

Regulatory T cells (Tregs) play a crucial role in the maintenance of peripheral tolerance. Quantitative and/or qualitative defects in Tregs result in diseases such as autoimmunity, allergy, malignancy, and graft-versus-host disease (GVHD), a serious complication of allogeneic stem cell transplantati...

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Publicat a:JCI Insight
Autors principals: Le Texier, Laëtitia, Lineburg, Katie E., Cao, Benjamin, McDonald-Hyman, Cameron, Leveque-El Mouttie, Lucie, Nicholls, Jemma, Melino, Michelle, Nalkurthi, Blessy C., Alexander, Kylie A., Teal, Bianca, Blake, Stephen J., Souza-Fonseca-Guimaraes, Fernando, Engwerda, Christian R., Kuns, Rachel D., Lane, Steven W., Teng, Michele, Teh, Charis, Gray, Daniel, Clouston, Andrew D., Nilsson, Susan K., Blazar, Bruce R., Hill, Geoffrey R., MacDonald, Kelli P.A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033749/
https://ncbi.nlm.nih.gov/pubmed/27699243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.86850
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