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Effects of MicroRNA on Regulatory T Cells and Implications for Adoptive Cellular Therapy to Ameliorate Graft-versus-Host Disease

Regulatory T cells (Tregs) are key mediators of the immune system. MicroRNAs (miRNAs) are a family of ~22 nucleotide non-coding RNAs that are processed from longer precursors by the RNases Drosha and Dicer. miRNA regulates protein expression posttranscriptionally through mRNA destabilization or tran...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hippen, Keli L., Loschi, Michael, Nicholls, Jemma, MacDonald, Kelli P. A., Blazar, Bruce R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797736/
https://ncbi.nlm.nih.gov/pubmed/29445371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00057
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