Donor colonic CD103(+) dendritic cells determine the severity of acute graft-versus-host disease

The primacy of the gastrointestinal (GI) tract in dictating the outcome of graft-versus-host disease (GVHD) is broadly accepted; however, the mechanisms controlling this effect are poorly understood. Here, we demonstrate that GVHD markedly enhances alloantigen presentation within the mesenteric lymp...

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izdano v:J Exp Med
Main Authors: Koyama, Motoko, Cheong, Melody, Markey, Kate A., Gartlan, Kate H., Kuns, Rachel D., Locke, Kelly R., Lineburg, Katie E., Teal, Bianca E., Leveque-El mouttie, Lucie, Bunting, Mark D., Vuckovic, Slavica, Zhang, Ping, Teng, Michele W.L., Varelias, Antiopi, Tey, Siok-Keen, Wockner, Leesa F., Engwerda, Christian R., Smyth, Mark J., Belz, Gabrielle T., McColl, Shaun R., MacDonald, Kelli P.A., Hill, Geoffrey R.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2015
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516799/
https://ncbi.nlm.nih.gov/pubmed/26169940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150329
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