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Eomesodermin Promotes the Development of Type-1 Regulatory T (T(R)1) Cells

Type-1 regulatory T (T(R)1) cells are Foxp3-negative IL-10-producing CD4(+) T cells with potent immune suppressive properties but their requirements for lineage development have remained elusive. Here we show that T(R)1 cells constitute the most abundant regulatory population after allogeneic bone m...

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Detalhes bibliográficos
Publicado no:Sci Immunol
Main Authors: Zhang, Ping, Lee, Jason S., Gartlan, Kate H., Schuster, Iona S, Comerford, Iain, Varelias, Antiopi, Ullah, Md Ashik, Vuckovic, Slavica, Koyama, Motoko, Kuns, Rachel D., Locke, Kelly R., Beckett, Kirrilee J., Olver, Stuart D., Samson, Luke D., de Oca, Marcela Montes, de Labastida Rivera, Fabian, Clouston, Andrew D., Belz, Gabrielle T., Blazar, Bruce R., MacDonald, Kelli P., McColl, Shaun R., Thomas, Ranjeny, Engwerda, Christian R., Degli-Esposti, Mariapia A., Kallies, Axel, Tey, Siok-Keen, Hill, Geoffrey R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714294/
https://ncbi.nlm.nih.gov/pubmed/28738016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aah7152
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