MHC class II antigen presentation by the intestinal epithelium initiates graft-versus-host disease and is influenced by the microbiota

Graft-versus-host disease (GVHD) in the gastrointestinal (GI) tract is the principal determinant of lethality following allogeneic bone marrow transplantation (BMT). Here, we examined the mechanisms that initiate GVHD, including the relevant antigen presenting cells. MHC-class-II was expressed on in...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Immunity
Päätekijät: Koyama, Motoko, Mukhopadhyay, Pamela, Schuster, Iona S, Henden, Andrea S, Hülsdünker, Jan, Varelias, Antiopi, Vetizou, Marie, Kuns, Rachel D, Robb, Renee J, Zhang, Ping, Blazar, Bruce R, Thomas, Ranjeny, Begun, Jakob, Waddell, Nicola, Trinchieri, Giorgio, Zeiser, Robert, Clouston, Andrew D, Degli-Esposti, Mariapia A, Hill, Geoffrey R
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959419/
https://ncbi.nlm.nih.gov/pubmed/31542340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.08.011
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia